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EpiGe-App (Epigenetic Genotyping Application) is an interactive, user-friendly web application for the classification of medulloblastoma WNT, SHH or non-WNT/non-SHH subgroups directly from quantitative PCR (qPCR) data (please see Quantitative PCR-based, methyl-genotyping assay protocol). The basis of this classification strategy is the analysis of the methylation profile of a previously validated panel of six CpG sites with distinctive, subgroup-specific methylation profiles (Gomez et al Clinical Cancer research 2018). The obtained raw qPCR data can be directly uploaded onto the EpiGe-App for automated interpretation of methylation status and subsequent subgroup prediction the methylation class of a medulloblastoma tumour. For further details, please Gómez et al iScience 2023.
EpiGe-App is a research tool that is intended only for scientific purposes: the EpiGe-App has not been validated clinically and was not designed for diagnostics purpose, nor to replace the services of a licensed, trained physician or health professional, or to substitute for medical advice.
This website is free and open to all users and there is no login requirement.
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Data uploaded to this website will only be stored in order to conduct the requested analyses. After 30 days the results and data of an analysis will be deleted. Please consult this page to get more information about data protection.